PSSD-Erectile dysfunction caused to ssri medications taken as anti depresssants

 

Post-SSRI Sexual Dysfunction (PSSD) is a condition that has garnered increasing attention in recent years due to its profound impact on individuals who have discontinued the use of selective serotonin reuptake inhibitors (SSRIs). SSRIs are commonly prescribed antidepressants known for their efficacy in treating mood disorders. However, for some individuals, the cessation of these medications does not mark the end of their side effects, particularly concerning sexual health.


Understanding PSSD

PSSD refers to the persistent sexual dysfunction that continues or emerges after stopping SSRIs. This condition is characterized by symptoms such as genital numbness, reduced libido, erectile dysfunction, and anorgasmia. What makes PSSD particularly distressing is its persistence; symptoms can last for months or even years after discontinuation of the medication. The European Medicines Agency recognized PSSD in 2019, acknowledging that sexual dysfunction can endure after stopping SSRI or SNRI treatment .​Verywell Health+1The Guardian+1PubMed+2BioMed Central+2The Guardian+2


Symptoms and Diagnosis

The hallmark symptoms of PSSD include:PSSD Network+5ScienceDirect+5PubMed+5

Diagnosing PSSD involves a thorough evaluation to rule out other potential causes of sexual dysfunction. According to the PSSD Network, necessary criteria include prior treatment with a serotonin reuptake inhibitor and an enduring change in genital sensation after treatment stops. Additional criteria encompass a reduction in sexual desire, erectile dysfunction, and an inability to orgasm, persisting for at least three months after discontinuation .​UK PSSD Association+1PSSD Network+1BioMed Central+4PSSD Network+4RxISK+4


Prevalence and Impact

The exact prevalence of PSSD remains uncertain, partly due to underreporting and misdiagnosis. A study highlighted that 13.2% of patients treated with antidepressants reported persistent post-treatment genital hypoesthesia, compared to 0.9% of those treated with other medications . The impact of PSSD on individuals is profound, affecting not only sexual health but also emotional well-being, relationships, and overall quality of life.RxISK+1PubMed+1


Potential Mechanisms

The pathophysiology of PSSD is not fully understood, but several theories have been proposed:PubMed

  • Neurotransmitter Imbalance: SSRIs increase serotonin levels, which may suppress dopamine, a neurotransmitter crucial for sexual function.

  • Receptor Downregulation: Chronic SSRI use may lead to downregulation of certain serotonin receptors, affecting sexual response.​

  • Epigenetic Changes: SSRIs might induce long-lasting changes in gene expression related to sexual function PubMed.​

  • Neurotoxicity: Some researchers suggest that SSRIs could have neurotoxic effects on pathways involved in sexual arousal and response PubMed.​


Treatment and Management

Currently, there is no universally accepted treatment for PSSD. Management strategies are largely symptomatic and may include:​

  • Pharmacological Interventions: Some patients have tried medications like bupropion, which has dopaminergic activity, with varying success.​

  • Psychotherapy: Addressing the psychological impact of PSSD through counseling or therapy can be beneficial.​

  • Lifestyle Modifications: Regular exercise, a healthy diet, and stress management techniques may help improve overall well-being.​

Research into treatments like low-power laser irradiation and phototherapy has shown some promise, but more studies are needed to establish efficacy ScienceDirect.​


Advocacy and Awareness

Organizations like the PSSD Network and the UK PSSD Association are working to raise awareness about the condition, advocate for research funding, and provide support to those affected. They emphasize the importance of informed consent when prescribing SSRIs, ensuring patients are aware of potential long-term side effects.UK PSSD Association+1The Guardian+1Verywell Health+1The Guardian+1


Conclusion

PSSD is a complex and often misunderstood condition that can have a significant impact on an individual's life. While SSRIs are effective for many in treating depression and anxiety, it's crucial to recognize and address the potential for persistent sexual side effects. Ongoing research, increased awareness, and patient advocacy are essential steps toward better understanding and managing PSSD.PubMed+1Verywell Health+1


References:

self respect| companies to treat individuals with proper respect

Self-respect is the cornerstone of a fulfilling life and a thriving workplace. It shapes how we perceive ourselves, interact with others, and navigate challenges. When individuals and organizations prioritize self-respect, they cultivate environments where dignity, productivity, and mutual appreciation flourish.


Understanding Self-Respect

At its core, self-respect involves recognizing one's inherent worth and maintaining a positive self-image. It's about setting boundaries, making decisions aligned with personal values, and treating oneself with kindness and dignity. This internal compass guides behavior, fosters resilience, and influences how others perceive and treat us.


The Role of Self-Respect in the Workplace

In professional settings, self-respect manifests in various ways:

  • Autonomy: Individuals with self-respect take initiative, make informed decisions, and accept responsibility for their actions.

  • Assertiveness: They communicate their ideas and needs confidently, fostering open and honest dialogue.

  • Resilience: Self-respecting employees handle setbacks constructively, viewing challenges as opportunities for growth.

These qualities contribute to a positive work environment, enhancing collaboration, innovation, and overall job satisfaction.


Companies That Prioritize Respect

Organizations that treat employees with respect reap significant benefits. For instance, Nvidia, a leading technology company, is renowned for its supportive work environment, flexible practices, and substantial employee benefits. Such an approach has been linked to higher employee satisfaction and improved financial performance.

Similarly, Teleperformance emphasizes treating employees as internal customers, focusing on mental health, diversity, and inclusion. Their commitment to employee well-being has earned them recognition as a top employer in India.TP | Digital Business Services+1Business Insider+1


Cultivating Self-Respect: Practical Steps

Building self-respect is an ongoing process that involves intentional actions:The Times of India+4Medium+4Question AI+4

  1. Set Boundaries: Clearly define your professional limits to maintain balance and prevent burnout.Medium

  2. Acknowledge Achievements: Celebrate your successes and recognize your contributions to foster a positive self-image.

  3. Continuous Learning: Invest in personal and professional development to enhance competence and confidence.

  4. Effective Communication: Express your thoughts clearly and listen actively to build mutual respect.

  5. Positive Self-Talk: Replace negative thoughts with affirmations that reinforce your value and capabilities.

Implementing these strategies can lead to increased productivity, job satisfaction, and a healthier work-life balance.Medium


The Impact of Respectful Workplaces

Workplaces that foster self-respect and mutual respect experience numerous advantages:

  • Enhanced Collaboration: Employees feel valued and are more willing to contribute ideas and support colleagues.

  • Higher Retention Rates: Respectful environments reduce turnover by promoting employee satisfaction and loyalty.

  • Improved Performance: A culture of respect motivates employees to perform at their best, driving organizational success.

By prioritizing respect, companies not only enhance employee well-being but also achieve better business outcomes.


Conclusion

Self-respect is integral to personal fulfillment and professional excellence. When individuals uphold their dignity and organizations cultivate respectful cultures, everyone benefits. Embracing self-respect leads to empowered employees, cohesive teams, and thriving businesses.The Times of India+4HRM online+4Medium+4

Ashwagandha | hair growth|how to have hair regrowth

Ashwagandha one of the best ayurvedic product of ancient times which has numerous benefits such as building muscles, hair growth, reduces stress, improves sex life etc.



                                                                  Ashwagandha contains antibacterial, anti-inflammatory, antifungal properties which help in treating scalp issues such as dandruff, scalp psoriasis, and itchiness.

                                                                   It contains protein ingredients that strengthen our hair and make our hair shaft less prone to breakage. Ashwagandha helps in blood circulation to scalp resulting in follicle stimulation which leads to more hair growth and is great at combating alopecia.



                                                                   Ashwagandha helps in stopping loss of melanin in hair shaft which prevents hair graying. It contains tyrosine which is the amino acid that stimulates melanin production and antioxidants within Ashwagandha which prevents corrosion of the tissues in the hair shaft.

Moto G6 Plus|review of Moto G6 Plus

Moto G6 Plus is now in stores whose amazign features are as follows:

Smart camera system a 15 cm(5.9) full HD + Max vision display with an 18:9 aspect ratio 6 GB of Ram and a blazing fast 2.2 GHz processor.


                                                                    

on-page optimization|benefits of on-page seo

what is SEO? SEO stands for search engine optimization part of digital marketing(online marketing) for product or services of a website(web pages).SEO is divided into category 1)on-page and off-page
Here we are going to know about on-page SEO. It is the strategy applied on webpage/website to make the site SEO friendly and attract users to site.

  Things included in on-page SEO are as follows:

1) keyword research
2)writing meta tags
3)writing content(content optimization)
4) image optimization
5)Url mapping
6)internal linking

After keyword research keywords are extracted or selected to be used on your website are kept in excel file which is used in further processes. Then Url mapping is done for the keywords and the pages need to be optimized in a website.

Using those keywords you can write meta tags such as title tags and description tags and keyword tags for pages which were mapped.keywords are used in the content for pages of 1000 words(content optimization)minimum including h1,h2,h3 header tags in the content.

We can use keywords in images using ALT tags for image optimization which is necessary to optimize as crawlers can't optimize image so Alt tags are used for image optimization using keywords.

Internal linking is linking of web pages in a website to increase authority of site by transfer of link juice came from link building(from backlinking from authoritative relevant sites) between pages in a website which increase the value of the website.For that, the site structure should be good enough that within3-4 clicks you can reach the internal links from home page which helps in ranking in google.

Finally you can use keywords in url which should be short for ranking.


The seo ranking factor you must master in 2018 and beyond

There is three SEO ranking factor you need to master in 2018 which are as follows:

1)bucket brigades:


2) Benefit-driven subheading


3)APP formula

why does motivation doesn't work for long ?|motivation speech|life motivation

Motivation is a short-term realization of achieving a goal which creates a sensation of success. Nowadays lot's of motivation speaker is there to give you life motivation and make you realize of achieving success.



                                                           People are aware of all sorts of things to get success because of the internet era because of lot's of the motivational programme is arranged. Then why do all people or the majority of people are not getting success?


                                                               Is destiny, luck fate is everything in getting success? Or there is some scope of human beings hard work is there to create his/her own destiny. Those people who are highly successful in there life may/may not wait for someone motivation or motivational speech to achieve success. Not they waited for the right time to come to achieve something.


                                                                          Even though destiny, fate is there something but without work/action no person can achieve greatness. Why Does human being is called as greatest of all creations of GOD? It's because Human beings are given with a brain whose power is still can't be measured, it's so powerful that human beings are above all creatures in the world and that's why if we compare to the past with the present lot's of things are invented which a logical brain can't think in the past, as people judge themselves in present or past information and get stuck in limited belief so they can't able to achieve greatness and shift there thinking to believe that some people are born to do all great things or born with special talent and rest of us are born to live a average or below average or to live a poor life.

                                                But if people's life is confined to there destiny then no use of called as greatest among all creatures as we also live like animals of limited possibilities. If GOD Has given a destiny/fate/luck like things which we learned here in this world but it is also a big truth that human beings can achieve bigger things in life if he is really willing to get and for that no motivation is required only by thinking or reading the achievements of others and why ur great than others creatures makes you believe that you can also do the impossible if you are willing to

                                                                        So to achieve success two important things are necessary that is what you want and belief to achieve that. Then accordingly other things come into the front that is clarity, direction, hard work.





Why complaining is bad?

Quit Whining. Nobody like to hear it and its bad for your health also. Complaining about half an hour damages a person's brain according to Stanford University. Whether you are listening or gripping it become a habit in your hippocampus(part of the brain for used for problem-solving or cognitive function).


                                                    If you are surrounded by complainers then we are likely to become one. We, people, complain much but not effectively says Guy winch Ph.D. and author of the squeaky wheel.

Google Analytics|Web analytics|google tracking

 What is Web Analytics?

Web Analytics is like a report card for your website. It helps you understand:

  • How many people visit your site

  • Where they come from (Google search, social media, ads, etc.)

  • What they do on your site (clicks, page views, purchases, etc.)

  • How long they stay and whether they come back

Think of it as your website’s fitness tracker—it shows you what’s working and what needs improvement.


📊 What is Google Analytics?

Google Analytics is a free tool by Google that does web analytics. It’s one of the most popular tools out there. Here’s what it helps you track:

  • User behavior (what pages they visit, how long they stay)

  • Traffic sources (where users came from)

  • Conversion rates (how many users signed up, bought something, etc.)

  • Devices used (mobile, desktop, tablet)

Basically, Google Analytics is the microscope that lets you see the fine details of what’s happening on your website.


🔍 What is Google Tracking?

Google Tracking is how Google Analytics collects the data. Here’s how it works:

  1. When someone visits your site, a small piece of code (called a tracking code) runs in the background.

  2. This code collects info about the visitor—like which page they visited, their location, device, and browser.

  3. That data gets sent to your Google Analytics dashboard.

This doesn’t collect personal info like names or passwords—just general behavior and tech data.


🤔 Why Does This Matter?

Understanding this helps you:

  • Make better decisions for your business or content strategy

  • Improve the user experience on your site

  • Spend your marketing money wisely

  • Know what content or products your visitors like most



                                                                  

Bounce rate| Google Analytics

Imagine someone walks into a store, looks around for a few seconds, and then walks right back out without touching or buying anything.

That’s a bounce.

In Google Analytics, a bounce happens when someone visits just one page on your website and leaves without doing anything else—no clicking, no scrolling to another page, no form-filling, nothing.

So, the bounce rate is the percentage of visitors who bounced.


💡 Real-Life Example:

Let’s say 100 people visit your homepage.

  • 70 of them leave without exploring any other pages.

  • 30 click around and visit other pages.

Your bounce rate = (70/100) × 100 = 70%


🧐 Why Do People Bounce?

People bounce for many reasons, like:

  • They didn’t find what they were looking for

  • Your site took too long to load

  • The content wasn’t engaging

  • They were just curious and not ready to act

  • The page did answer their question, and they didn’t need more


📉 Is a High Bounce Rate Bad?

Not always. It depends on your goals.

  • Blog posts? A high bounce rate might be okay—people read the article and leave.

  • E-commerce? Not good—you want people to browse, add to cart, and buy.

  • Landing pages? Depends—if they came, clicked a call-to-action (like a phone number or form), and left, that might still be a win.


🚀 How Can You Reduce Bounce Rate?

Here are a few human-friendly tips:

  • Make your content relevant to what users expect

  • Improve page load speed (nobody likes waiting)

  • Add internal links to guide them to more content

  • Use clear CTAs (Calls To Action)

  • Optimize for mobile (lots of bounces come from bad mobile experiences)


📌 TL;DR:

Bounce Rate = People who visit one page and leave without doing anything.
It helps you understand user interest and content engagement.

Page views|Google Analytics

A page view is defined as the total number of pages visited by all people on a website.In other words, it is called a hit. Repeated views of a page are also counted.



Page views can tell how popular is a page or post is.


Unique Page views is a single visit for a page is counted  as unique page views not counted a page more than once.

session|google analytics

What do u mean by Session? Session means when a user/visitor visits your website and interactions done by a user such as social interactions, page views, events, e-commerce transactions in a single time frame.


                                                 You can understand session as a container for actions a user takes on your site.



A single user can open multiple sessions during those sessions can occur one a single day or over a period of time of several days, weeks or months. As a session ends a new session can start on the next visit.

There are two methods by which a session ends
1)Time-based expiration
a)After 30 min inactivity
b)At midnight
2)Campaign change

Time-based expiration :

How long the session lasts?

A session lasts for 30 mins of inactivity. But you can adjust this limit from a few secs to several hours.
example: Suppose a user visit your site and leaves your site and comes after 30 mins again then it will be called as 2 sessions as 2 visits by the user. But if the user continues  and interacts with the website then it will be called as 1 session






Advanced startegies of seo 2018

SEO stands for search engine optimization which makes website rank in search engine organically and gets traffic and increases sales.SEO is one of the best digital marketing technique done to get organic traffic.


                                                             SEO consists of ON-PAGE and OFF-PAGE optimization, SEO is done on the website to highlight services or product offered by the website or the company or organization. After the internet is widely used all over the world people prefer everything online whether to buy a product or see the information before buying.



                                                                 Digital marketing is marketing done online which gives information about customers and there demands easily rather than the previous way of direct marketing.SEO is done nowadays for every website to advertise there product and services and spread awareness near people through easy channel online.


                                                                      Here we are going to know about what are advanced strategies of SEO of 2018 which gives a boost to your website and get ranking and leads in search engine which is as follows:

1)site loading speed should be good for the user and for google or else google penalized slow loading speed and also traffic doesn't come.

it can be checked to by google page speed insights tool of google where site speed can be known.

to know more accurate load speed you can go for GT METRIX tool where you can get actual loading speed and rectify mistakes to get solved.

2) Go to google webmaster tool for checking technical issues such as crawl errors and check it fully and fix the issues.

3)Keyword research: Which is done by many tools such as google suggest where Google can suggest the keywords which are been searched and you can check the volume and bidding in google keyword planner tool and extract from them the suitable keywords but to get the accurate volume you use Semrush tool.

you can go for google webmaster tool in search analytics and get the keywords which are ranking

4)Content Development: You have to create unique content for your website which must be actionable(highly practical) by using the competitive keywords.

                                                                  You must make sure your content should be 1890 words(average). Make infographics in part of the content to get more visits and get viral.

5)On-Page SEO: We should optimize content, URLs, H1, H2, H3 TAGs with Target keywords to optimize and make URLs short and simple for ranking.

                                                                  Include your target keyword in Ist 100 words of content to make Google understand what the topic is all about. And use outbound links relevant links of authoritative sites are also considered in Google algorithms and do have a positive impact in rankings.

6)Link Building SEO : Link building is very essential in ranking .where you get inbound links from authoritative sites which has lot external links and find a page where broken links are there and ask them in the mail about that, tell them about ur content of page which can add some value to their website and get link from that page of Authoritative site.which will helps you in ranking .

7)User experience: How the user is interacting with your site which can be known by Google analytics can make you aware in ranking and less the bounce rate and high CTR is the ranking factor.











keyword density

keyword density is the density of keywords used in a content of individual web pages in a website. keyword density should be 3-5 % in a content more than that will be called as keyword stuffing which comes under negative  SEO. which google will give the penalty as it comes against google rules.



                                                             Keyword density is checked for content by tool keyword density checker where it will show what is the density of particular keyword accordingly we have to arrange keywords in a content and we should not overstuff keywords in a content where relevance is not there.

Internal linking seo|online advertising|seo online services

What is internal linking ?? Internal linking is making web pages linked with each other in a  website through extracted keywords found through keyword research and URLs.





                                                       Internal linking gives navigation to the user in a website. It makes a crawler to follow the link paths and crawling will be easy as a result indexing will be easy. if you make a strong linking structure you will get linking juice earning a potential of internal pages by clicking indexation throughout the website.



                                                           Internal linking spreads the strength of website to internal pages. When a website gets an inbound link to homepage some of its link juice is passed to internal pages. And it is one of the advanced strategies of SEO which helps in boosting the site in getting rank and strength of a website as URLs are interlinked in a website.



                                                              After URL MAPPING is done we have to arrange keywords with the URLs by its product or services offered by a particular page in a website and the navigation is done by used keywords in that particular page to the other pages where it matches according to relevance. As I used URL MAPPING keyword with another post of detailed information of URL MAPPING.

how to do url mapping

Url mapping is done with keywords extracted through keyword suggestions tool and the URLs of the website which you need to optimize.


Then map the keywords with URLs according to relevance.




So that using that keyword according to respective URLs we use in meta tags and content accordingly.

just for example


keywords  are mapped for URLs following:

                         abc---------------------------------->www.domain.com/ews

                        bcd--------------------------------->www.domain.com/gfdsk

                        cde--------------------------------->www.domain.com/kgh
                        fgh---------------------------------->www.domain.com/ssd




Then particular keywords are used in relavant urls which are mapped as above

Meta tags

After keyword analysis when keywords are extracted they are used in Meta tags which consist of the title tag, description tag, keywords tags


title tags consist of 70 characters using primary and secondary  keywords with | signs found through keyword research

description tags consist of  300 characters using keywords defining a small description of the webpage in short which is used for user purpose, not for search rankings which help in traffic to your website.

keyword tags also are the keywords used in the webpage.

how to do keyword research

Keyword research is a term used in search engine optimization, for extracting keywords used for your website. Which is done by using different tools such as keyword planner, semrush etc.


                                                                       Well, how to do keyword research? ist take some keywords in the user point of view according to your website niche and put in keyword planner tool, take some keywords from google suggest the most searched keywords of your niche and some keywords in the down of SERP page and check the volume and competition in planner tool.





select the keywords according to most searched volume and less competitive keywords in keyword planner and extract in excel file sheet.




                                                       Make a final list of keywords for your website with some long tail keywords to use it in content and get leads.


                                                                   This is a basic way of searching keywords for a website and rest more you practice you can able to learn better .or else you can use paid tool such as semrush to get more accurate results for keyword research 

PSSD-Erectile dysfunction caused to ssri medications taken as anti depresssants

  Post-SSRI Sexual Dysfunction (PSSD) is a condition that has garnered increasing attention in recent years due to its profound impact on in...